Use of Dehydrated Amniotic Membrane in Wound Management
Use of Dehydrated Amniotic Membrane in Wound Management
Human amniotic membrane is a uniquely suited material for use as an allograft in wound management. Used in its natural form, then later in preserved preparations, the material assists in the healing process through a number of physical, biochemical and molecular biological pathways to promote regenerative healing while simultaneously reducing scar formation. Dramatic wound closure rates have been demonstrated for chronic wounds, while evolving characterization of the mechanisms involved indicate deep involvement of the molecular biology of the healing process that is occurring. Wounds respond best to advanced therapies, such as dHAM, when utilized early in the treatment regime; the PAR Tool elucidated in this manuscript may help make appropriate decisions in this regard. Additional research and characterization of this process will more completely define the dramatic results seen in the application of this material.
Conclusion
Human amniotic membrane is a uniquely suited material for use as an allograft in wound management. Used in its natural form, then later in preserved preparations, the material assists in the healing process through a number of physical, biochemical and molecular biological pathways to promote regenerative healing while simultaneously reducing scar formation. Dramatic wound closure rates have been demonstrated for chronic wounds, while evolving characterization of the mechanisms involved indicate deep involvement of the molecular biology of the healing process that is occurring. Wounds respond best to advanced therapies, such as dHAM, when utilized early in the treatment regime; the PAR Tool elucidated in this manuscript may help make appropriate decisions in this regard. Additional research and characterization of this process will more completely define the dramatic results seen in the application of this material.
