The first you must do is to create a link before thinking of wooing a girl. Your goal is to lay the groundwork for success, not a rejection. Once you decide which woman you want to pick up, the first step is to make eye contact with her. After that you smile or say hello, you can know she is interested also by her response, if it is a positive gesture. if she gives you a semi-smile and looks away quickly, then try someone else.
First make the connection, and then play hard. Basically, you should not act as if you were desperate to meet someone. If this is the place for it then ask her to join you in a dance. If she responds positively, the initial link was formed, with the next already being made. Have a good time while you are dancing. Just enjoy and remember that she is going to pick up on your discomfort. Dancing together is truly a fine initial step in order to take you up the ladder of relations because dancing has the attribute of ease all the hesitations and stress, you both might be having initially.
If you can dance well she will use that as a thermometer for any other of your skills. It's essential that you have fun, when you are done dancing thank the girl, walk her back to her table then walk away. Don't do what she expects you to do, play hard to get once she expresses her interest. If you came with friends, continue laughing with them working the crowd as you go. Dancing with other girls is ok, but save your sexy moves for the one you want to take home. Make every move by exhibiting confidence. Everything matters, even simple actions like having your drink and reaching the dance arena.
A woman will discern your lack of self-assurance if you do not believe that you are the best man in the room, thus how to pick up girls won't be your primary concern but how to build your self-belief will be. A man who carries himself proudly is very attractive to women.
Make sure you don't cross the line from self-confidence into arrogance. Self confidence is important, as it can show that you can love someone else since you love yourself. Arrogance implies that one believes they are better than everyone else, which is a turn off and unrealistic mind set. Making the connection first greatly increases your chances of success with girls.
Inviting her on the dance floor is your next step. And last, but certainly not least, once you've spent the better part of the evening flitting about the room and playing hard to get, approach her and tell her that you'd like to leave this place and find somewhere else in which the two of you can get better acquainted. If she agrees, don't be so shocked.