Asbestos Cause Mesothelioma And Cancer Gene Mutation
Asbestos is a generic term for natural mineral fiber. Danger of serious damage to health by prolonged asbestos exposure. The association between asbestos exposure and bronchogenic carcinoma is now accepted as being causal in nature.
Tumor-suppressor genes normally protect cells from becoming cancerous, but the gradual silencing of these genes by abnormal methylation is thought to be an early change in cancer deelopment. The study of asbestos cause cancer Is mainly about the physical and chemical properties of asbestos. Oncogenes are regarded With the discovery of oncogenes in the study of cell transformation. Late 1980s, people began to study the cause of asbestos cancer. Asbestos can induce cell chromosome aberration. Chromosome aberrance probably are the cytological elements causing mesothelioma cancer. The asbestos cancer have a very long incubation period. The incubation period of malignant mesothelioma up to 40 years. The cell undergoes include changes in multiple gene loci. Although there are many cancer genes have been found, mesothelioma cancer gene only include ras, c-fos, c-jun, sis, etc. Gene in normal human body, there is a class called proto-oncogenes, and the other called tumor suppressor gene. The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on. There are many Proto-oncogene is activated and the loss of tumor suppressor genes, on the onset and developing of mesothelioma, often with people's lifestyles and behavior of external factors. Under normal circumstances, they are sealed in a fixed state, but in exceptional circumstances, the proto-oncogenes or tumor suppressor genes are activated is lost, people will suffer from cancer. Asbestos induce reactive oxygen species in the process of asbestos cause cancer, the distortion fo chromosome number and structure were caused by gene mutations. The development of tumor involves in many factors, such as activating of oncogene, invalidating of cancer suppressor genes and abnormal expressing of apoptosis genes.
Mesothelioma's long latency has proven more loci change in the process of asbestos cause cancer. Researchers to find out which genes can cause mesothelioma is a long term task. A new study from the National Institutes of Healths National Cancer Institute has made a new connection between genetic mutations and an individuals susceptibility to developing mesothelioma at some point in their life.
Tumor-suppressor genes normally protect cells from becoming cancerous, but the gradual silencing of these genes by abnormal methylation is thought to be an early change in cancer deelopment. The study of asbestos cause cancer Is mainly about the physical and chemical properties of asbestos. Oncogenes are regarded With the discovery of oncogenes in the study of cell transformation. Late 1980s, people began to study the cause of asbestos cancer. Asbestos can induce cell chromosome aberration. Chromosome aberrance probably are the cytological elements causing mesothelioma cancer. The asbestos cancer have a very long incubation period. The incubation period of malignant mesothelioma up to 40 years. The cell undergoes include changes in multiple gene loci. Although there are many cancer genes have been found, mesothelioma cancer gene only include ras, c-fos, c-jun, sis, etc. Gene in normal human body, there is a class called proto-oncogenes, and the other called tumor suppressor gene. The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on. There are many Proto-oncogene is activated and the loss of tumor suppressor genes, on the onset and developing of mesothelioma, often with people's lifestyles and behavior of external factors. Under normal circumstances, they are sealed in a fixed state, but in exceptional circumstances, the proto-oncogenes or tumor suppressor genes are activated is lost, people will suffer from cancer. Asbestos induce reactive oxygen species in the process of asbestos cause cancer, the distortion fo chromosome number and structure were caused by gene mutations. The development of tumor involves in many factors, such as activating of oncogene, invalidating of cancer suppressor genes and abnormal expressing of apoptosis genes.
Mesothelioma's long latency has proven more loci change in the process of asbestos cause cancer. Researchers to find out which genes can cause mesothelioma is a long term task. A new study from the National Institutes of Healths National Cancer Institute has made a new connection between genetic mutations and an individuals susceptibility to developing mesothelioma at some point in their life.
