What Do We Know About Managing BP in Patients With CKD?
What Do We Know About Managing BP in Patients With CKD?
Evidence for the management of BP after kidney transplantation is limited. The few trials that have been conducted have tended to study interventions during the first year post transplantation and have been of short duration. Most of these trials did not fulfill the prespecified criteria for inclusion in the evidence review. On balance, the Work Group felt that the target BP in these patients should be ≤130/80 mm Hg regardless of other factors, in keeping with the recommendation published in another KDIGO guideline focussed on care of the transplant recipient. With respect to individualizing therapy, the Work Group recognized that time after transplantation, the use of calcineurin inhibitors, the presence of albuminuria, and other comorbidities may influence the choice of the BP-lowering agent, but were unable to be any more precise on this issue owing to the lack of robust clinical trials assessing relevant clinical endpoints.
How Should Blood Pressure Be Managed in Kidney Transplant Recipients?
Evidence for the management of BP after kidney transplantation is limited. The few trials that have been conducted have tended to study interventions during the first year post transplantation and have been of short duration. Most of these trials did not fulfill the prespecified criteria for inclusion in the evidence review. On balance, the Work Group felt that the target BP in these patients should be ≤130/80 mm Hg regardless of other factors, in keeping with the recommendation published in another KDIGO guideline focussed on care of the transplant recipient. With respect to individualizing therapy, the Work Group recognized that time after transplantation, the use of calcineurin inhibitors, the presence of albuminuria, and other comorbidities may influence the choice of the BP-lowering agent, but were unable to be any more precise on this issue owing to the lack of robust clinical trials assessing relevant clinical endpoints.