CMV-Associated Splenic Infarcts in an Immune-Competent
CMV-Associated Splenic Infarcts in an Immune-Competent
Introduction: Cytomegalovirus-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has been rarely mentioned.
Case presentation: We report the case of a 38-year-old Caucasian man of Hellenic origin with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Echocardiography did not show any vegetations or mural thrombi. Anticoagulation treatment was not considered due to implication of minor vessels and since cytomegalovirus was the probable trigger for thrombosis in this patient.
Conclusions: This case report serves as additional evidence for the role of cytomegalovirus in thrombosis.
Acute infection with cytomegalovirus (CMV) is usually asymptomatic or may present as an infectious mononucleosis like-syndrome. In the immune-compromised patient, however, the clinical setting of the disease can be expressed with various life-threatening conditions. CMV-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has been rarely mentioned. While most reports of CMV-associated thrombosis are referring to immune-compromised transplant recipients or human immunodeficiency virus (HIV)-positive patients, we report a case of acute CMV infection in an immune-competent patient, presenting with spontaneous spleen infarcts.
Abstract and Introduction
Abstract
Introduction: Cytomegalovirus-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has been rarely mentioned.
Case presentation: We report the case of a 38-year-old Caucasian man of Hellenic origin with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Echocardiography did not show any vegetations or mural thrombi. Anticoagulation treatment was not considered due to implication of minor vessels and since cytomegalovirus was the probable trigger for thrombosis in this patient.
Conclusions: This case report serves as additional evidence for the role of cytomegalovirus in thrombosis.
Introduction
Acute infection with cytomegalovirus (CMV) is usually asymptomatic or may present as an infectious mononucleosis like-syndrome. In the immune-compromised patient, however, the clinical setting of the disease can be expressed with various life-threatening conditions. CMV-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has been rarely mentioned. While most reports of CMV-associated thrombosis are referring to immune-compromised transplant recipients or human immunodeficiency virus (HIV)-positive patients, we report a case of acute CMV infection in an immune-competent patient, presenting with spontaneous spleen infarcts.
